Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer's Disease: In Vitro and In Vivo Evidence

Alzheimer's disease (AD) is a neurodegenerative disorder responsible for the majority of dementia cases in elderly people. It is widely accepted that the main hallmarks of AD are not only senile plaques and neurofibrillary tangles but also reactive astrogliosis, which often precedes detrimental...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Bronzuoli, Maria Rosanna, Facchinetti, Roberta, Steardo, Luca, Romano, Adele, Stecca, Claudia, Passarella, Sergio, Cassano, Tommaso, Scuderi, Caterina
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822864/
https://ncbi.nlm.nih.gov/pubmed/29576849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4720532
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