Ultramicronized palmitoylethanolamide rescues learning and memory impairments in a triple transgenic mouse model of Alzheimer’s disease by exerting anti-inflammatory and neuroprotective effects

In an aging society, Alzheimer’s disease (AD) exerts an increasingly serious health and economic burden. Current treatments provide inadequate symptomatic relief as several distinct pathological processes are thought to underlie the decline of cognitive and neural function seen in AD. This suggests...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Scuderi, Caterina, Bronzuoli, Maria Rosanna, Facchinetti, Roberta, Pace, Lorenzo, Ferraro, Luca, Broad, Kevin Donald, Serviddio, Gaetano, Bellanti, Francesco, Palombelli, Gianmauro, Carpinelli, Giulia, Canese, Rossella, Gaetani, Silvana, Steardo, Luca, Cassano, Tommaso
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802581/
https://ncbi.nlm.nih.gov/pubmed/29382825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0076-4
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