Retinal Architecture and Melanopsin-Mediated Pupillary Response Characteristics: A Putative Pathophysiologic Signature for the Retino-Hypothalamic Tract in Multiple Sclerosis

IMPORTANCE: A neurophysiologic signature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with potential utility for investigating alterations in homeostatic mechanisms associ...

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Bibliografske podrobnosti
izdano v:JAMA Neurol
Main Authors: Meltzer, Ethan, Sguigna, Peter V., Subei, Adnan, Beh, Shin, Kildebeck, Eric, Conger, Darrel, Conger, Amy, Lucero, Marlen, Frohman, Benjamin S., Frohman, Ashley N., Saidha, Shiv, Galetta, Steven, Calabresi, Peter A., Rennaker, Robert, Frohman, Teresa C., Kardon, Randy H., Balcer, Laura J., Frohman, Elliot M.
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2017
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822208/
https://ncbi.nlm.nih.gov/pubmed/28135360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.5131
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