Retinal Architecture and Melanopsin-Mediated Pupillary Response Characteristics: A Putative Pathophysiologic Signature for the Retino-Hypothalamic Tract in Multiple Sclerosis

IMPORTANCE: A neurophysiologic signature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with potential utility for investigating alterations in homeostatic mechanisms associ...

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Dades bibliogràfiques
Publicat a:JAMA Neurol
Autors principals: Meltzer, Ethan, Sguigna, Peter V., Subei, Adnan, Beh, Shin, Kildebeck, Eric, Conger, Darrel, Conger, Amy, Lucero, Marlen, Frohman, Benjamin S., Frohman, Ashley N., Saidha, Shiv, Galetta, Steven, Calabresi, Peter A., Rennaker, Robert, Frohman, Teresa C., Kardon, Randy H., Balcer, Laura J., Frohman, Elliot M.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2017
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822208/
https://ncbi.nlm.nih.gov/pubmed/28135360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.5131
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