Retinal Architecture and Melanopsin-Mediated Pupillary Response Characteristics: A Putative Pathophysiologic Signature for the Retino-Hypothalamic Tract in Multiple Sclerosis

IMPORTANCE: A neurophysiologic signature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with potential utility for investigating alterations in homeostatic mechanisms associ...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Meltzer, Ethan, Sguigna, Peter V., Subei, Adnan, Beh, Shin, Kildebeck, Eric, Conger, Darrel, Conger, Amy, Lucero, Marlen, Frohman, Benjamin S., Frohman, Ashley N., Saidha, Shiv, Galetta, Steven, Calabresi, Peter A., Rennaker, Robert, Frohman, Teresa C., Kardon, Randy H., Balcer, Laura J., Frohman, Elliot M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822208/
https://ncbi.nlm.nih.gov/pubmed/28135360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.5131
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