Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis: Neurofilament Light Chain Levels in Definite Subtypes of Disease

IMPORTANCE: A clearer definition of the role of neurofilament light chain (NFL) as a biomarker in amyotrophic lateral sclerosis (ALS) is needed. OBJECTIVES: To assess the ability of NFL to serve as a diagnostic biomarker in ALS and the prognostic value of cerebrospinal fluid NFL in patients with ALS...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Gaiani, Alessandra, Martinelli, Ilaria, Bello, Luca, Querin, Giorgia, Puthenparampil, Marco, Ruggero, Susanna, Toffanin, Elisabetta, Cagnin, Annachiara, Briani, Chiara, Pegoraro, Elena, Sorarù, Gianni
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822207/
https://ncbi.nlm.nih.gov/pubmed/28264096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.5398
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