Beyond the Traditional Clinical Trials for Amyotrophic Lateral Sclerosis and The Future Impact of Gene Therapy

Amyotrophic lateral sclerosis (ALS) is a devastating and incurable motor neuron (MN) disorder affecting both upper and lower MNs. Despite impressive advances in the understanding of the disease’s pathological mechanism, classical pharmacological clinical trials failed to provide an efficient cure fo...

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Bibliografiske detaljer
Udgivet i:J Neuromuscul Dis
Main Authors: Cappella, Marisa, Pradat, Pierre-François, Querin, Giorgia, Biferi, Maria Grazia
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902976/
https://ncbi.nlm.nih.gov/pubmed/33074186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JND-200531
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