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Beyond the Traditional Clinical Trials for Amyotrophic Lateral Sclerosis and The Future Impact of Gene Therapy

Amyotrophic lateral sclerosis (ALS) is a devastating and incurable motor neuron (MN) disorder affecting both upper and lower MNs. Despite impressive advances in the understanding of the disease’s pathological mechanism, classical pharmacological clinical trials failed to provide an efficient cure fo...

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Detalhes bibliográficos
Publicado no:J Neuromuscul Dis
Main Authors: Cappella, Marisa, Pradat, Pierre-François, Querin, Giorgia, Biferi, Maria Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902976/
https://ncbi.nlm.nih.gov/pubmed/33074186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JND-200531
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