HAP1 Is Required for Endocytosis and Signalling of BDNF and Its Receptors in Neurons

When BDNF binds to its receptors, TrkB and p75(NTR), the BDNF-receptor complex is endocytosed and trafficked to the cell body for downstream signal transduction, which plays a critical role in neuronal functions. Huntingtin-associated protein 1 (HAP1) is involved in trafficking of vesicles intracell...

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Bibliografski detalji
Izdano u:Mol Neurobiol
Glavni autori: Lim, Yoon, Wu, Linda Lin-Yan, Chen, Si, Sun, Ying, Vijayaraj, Swarna Lekha, Yang, Miao, Bobrovskaya, Larisa, Keating, Damien, Li, Xiao-Jiang, Zhou, Xin-Fu
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821608/
https://ncbi.nlm.nih.gov/pubmed/28083816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-0379-0
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