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UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer

Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The ubiquitin receptor protein Ubiquitin Associated and SH3 Domain Containing B (UBASH3B) was recentl...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Krupina, Ksenia, Kleiss, Charlotte, Awal, Sushil, Rodriguez-Hernandez, Irene, Sanz-Moreno, Victoria, Sumara, Izabela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821415/
https://ncbi.nlm.nih.gov/pubmed/29487893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1271494
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