Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)

Two SIVmac251-infected rhesus macaques received tenofovir/emtricitabine with raltegravir intensification. Viral rebound occurred during treatment and sequencing of reverse transcriptase and integrase genes identified multiple resistance mutations. Similar to HIV infection, antiretroviral-resistance...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Policicchio, Benjamin Bruno, Sette, Paola, Xu, Cuiling, Haret-Richter, George, Dunsmore, Tammy, Pandrea, Ivona, Ribeiro, Ruy M., Apetrei, Cristian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821307/
https://ncbi.nlm.nih.gov/pubmed/29466356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190908
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