Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision

Membrane lipid composition is central to the highly specialized functions of neurological tissues. In the retina, abnormal lipid metabolism causes severe forms of blindness, often through poorly understood neuronal cell death. Here, we demonstrate that deleting the de novo lipogenic enzyme fatty aci...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Rajagopal, Rithwick, Zhang, Sheng, Wei, Xiaochao, Doggett, Teresa, Adak, Sangeeta, Enright, Jennifer, Shah, Vaishali, Ling, Guoyu, Chen, Shiming, Yoshino, Jun, Hsu, Fong-Fu, Semenkovich, Clay F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821215/
https://ncbi.nlm.nih.gov/pubmed/29321376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97076
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