Noninvasive gene delivery to foveal cones for vision restoration

Intraocular injection of adeno-associated viral (AAV) vectors has been an evident route for delivering gene drugs into the retina. However, gaps in our understanding of AAV transduction patterns within the anatomically unique environments of the subretinal and intravitreal space of the primate eye i...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Khabou, Hanen, Garita-Hernandez, Marcela, Chaffiol, Antoine, Reichman, Sacha, Jaillard, Céline, Brazhnikova, Elena, Bertin, Stéphane, Forster, Valérie, Desrosiers, Mélissa, Winckler, Céline, Goureau, Olivier, Picaud, Serge, Duebel, Jens, Sahel, José-Alain, Dalkara, Deniz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821199/
https://ncbi.nlm.nih.gov/pubmed/29367457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96029
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