Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction

Crohn’s disease (CD) is a chronic inflammatory disease of the gastrointestinal tract (GIT). Cigarette smoke (CS) exposure and chronic obstructive pulmonary disease (COPD) are risk factors for CD, although the mechanisms involved are poorly understood. We employed a mouse model of CS-induced experime...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Fricker, Michael, Goggins, Bridie J., Mateer, Sean, Jones, Bernadette, Kim, Richard Y., Gellatly, Shaan L., Jarnicki, Andrew G., Powell, Nicholas, Oliver, Brian G., Radford-Smith, Graham, Talley, Nicholas J., Walker, Marjorie M., Keely, Simon, Hansbro, Philip M.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821186/
https://ncbi.nlm.nih.gov/pubmed/29415878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94040
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