TNF receptor–activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling

To elucidate the mechanisms responsible for cytoprotective effects of TNF receptor–activated factor 2 (TRAF2) in the heart, we employed genetic gain- and loss-of-function studies ex vivo and in vivo in mice with cardiac-restricted overexpression of TRAF2 (Myh6-TRAF2(LC)). Crossing Myh6-TRAF2(LC) mic...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Evans, Sarah, Tzeng, Huei-Ping, Veis, Deborah J., Matkovich, Scot, Weinheimer, Carla, Kovacs, Attila, Barger, Philip M., Mann, Douglas L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821173/
https://ncbi.nlm.nih.gov/pubmed/29415884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98278
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki