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MiR-21-mediated Metabolic Alteration of Cancer-associated Fibroblasts and Its Effect on Pancreatic Cancer Cell Behavior

In this study, we investigated whether the metabolic alteration of cancer-associated fibroblasts (CAFs) occurs via miR-21 remodeling and the effect of this alteration on pancreatic cancer cells. CAFs and normal fibroblasts (NFs) were isolated and cultured. Glucose consumption and lactic acid product...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Chen, Shuo, Chen, Xi, Shan, Tao, Ma, Jiancang, Lin, Wanrun, Li, Wei, Kang, Ya'an
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821053/
https://ncbi.nlm.nih.gov/pubmed/29483829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.22555
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