Evaluation of CpxRA as a Therapeutic Target for Uropathogenic Escherichia coli Infections

CpxRA is an envelope stress response system found in all members of the family Enterobacteriaceae; CpxA has kinase activity for CpxR and phosphatase activity for phospho-CpxR, a transcription factor. CpxR also accepts phosphate groups from acetyl phosphate, a glucose metabolite. Activation of CpxR i...

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Vydáno v:Infect Immun
Hlavní autoři: Dbeibo, Lana, van Rensburg, Julia J., Smith, Sara N., Fortney, Kate R., Gangaiah, Dharanesh, Gao, Hongyu, Marzoa, Juan, Liu, Yunlong, Mobley, Harry L. T., Spinola, Stanley M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820967/
https://ncbi.nlm.nih.gov/pubmed/29311237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00798-17
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