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The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells

BACKGROUND: We aimed to investigate the effect and mechanism of curcumin (CUR) in Alzheimer's disease (AD). METHODS: Mouse hippocampal neuronal cell line HT-22 was treated with Aβ1–42 and/or CUR, and then cell viability was evaluated by cell counting kit 8, Beclin-l level was detected using wes...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zhang, Lu, Fang, Yu, Cheng, Xuan, Lian, Yajun, Zeng, Zhaoshu, Wu, Chuanjie, Zhu, Hongcan, Xu, Hongliang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820551/
https://ncbi.nlm.nih.gov/pubmed/29568765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8134902
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