Nalaganje...

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

Fractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway contribute to NTDs in humans and mice, but whether this pathway independently determines bone mass is poorly understood. Here, we first confirmed tha...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Orriss, Isabel R., Lanham, Stuart, Savery, Dawn, Greene, Nicholas D. E., Stanier, Philip, Oreffo, Richard, Copp, Andrew J., Galea, Gabriel L.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820290/
https://ncbi.nlm.nih.gov/pubmed/29463853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21718-x
Oznake: Označite
Brez oznak, prvi označite!