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Mutations in Planar Cell Polarity Gene SCRIB Are Associated with Spina Bifida

Neural tube defects (NTDs) (OMIM #182940) including anencephaly, spina bifida and craniorachischisis, are severe congenital malformations that affect 0.5–1 in 1,000 live births in the United States, with varying prevalence around the world. Mutations in planar cell polarity (PCP) genes are believed...

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Detalhes bibliográficos
Main Authors: Lei, Yunping, Zhu, Huiping, Duhon, Cody, Yang, Wei, Ross, M. Elizabeth, Shaw, Gary M., Finnell, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724847/
https://ncbi.nlm.nih.gov/pubmed/23922697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069262
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