Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity

A common complication of diabetes is distal symmetric polyneuropathy, which causes symptoms such as numbness, tingling and pain due to sensory axon degeneration. The mechanisms leading to degeneration remain incompletely understood but reactive oxygen species (ROS) that are formed by lipid oxidation...

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Udgivet i:J Diabetes Complications
Main Authors: Waldron, Ashley L., Schroder, Patricia A., Bourgon, Kelly L., Bolduc, Jessie K., Miller, James L., Pellegrini, Adriana D., Dubois, Amanda L., Blaszkiewicz, Magdalena, Townsend, Kristy L., Rieger, Sandra
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820202/
https://ncbi.nlm.nih.gov/pubmed/29306589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2017.11.012
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