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Protein contact prediction by integrating deep multiple sequence alignments, coevolution and machine learning

In this work, we report the evaluation of the residue-residue contacts predicted by our three different methods in the CASP12 experiment, focusing on studying the impact of multiple sequence alignment, residue coevolution and machine learning on contact prediction. The first method (MULTICOM-NOVEL)...

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Dettagli Bibliografici
Pubblicato in:Proteins
Autori principali: Adhikari, Badri, Hou, Jie, Cheng, Jianlin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820155/
https://ncbi.nlm.nih.gov/pubmed/29047157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25405
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