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Protein contact prediction by integrating deep multiple sequence alignments, coevolution and machine learning

In this work, we report the evaluation of the residue-residue contacts predicted by our three different methods in the CASP12 experiment, focusing on studying the impact of multiple sequence alignment, residue coevolution and machine learning on contact prediction. The first method (MULTICOM-NOVEL)...

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Foilsithe in:Proteins
Main Authors: Adhikari, Badri, Hou, Jie, Cheng, Jianlin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820155/
https://ncbi.nlm.nih.gov/pubmed/29047157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25405
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