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Protein contact prediction by integrating deep multiple sequence alignments, coevolution and machine learning

In this work, we report the evaluation of the residue-residue contacts predicted by our three different methods in the CASP12 experiment, focusing on studying the impact of multiple sequence alignment, residue coevolution and machine learning on contact prediction. The first method (MULTICOM-NOVEL)...

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Vydáno v:Proteins
Hlavní autoři: Adhikari, Badri, Hou, Jie, Cheng, Jianlin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820155/
https://ncbi.nlm.nih.gov/pubmed/29047157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25405
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