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Application of methyl-TROSY to a large paramagnetic membrane protein without perdeuteration: (13)C-MMTS-labeled NADPH-cytochrome P450 oxidoreductase

NMR spectroscopy of membrane proteins involved in electron transport is difficult due to the presence of both the lipids and paramagnetic centers. Here we report the solution NMR study of the NADPH-cytochrome P450 oxidoreductase (POR) in its reduced and oxidized states. We interrogate POR, first, in...

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Detalhes bibliográficos
Publicado no:J Biomol NMR
Main Authors: Galiakhmetov, Azamat R, Kovrigina, Elizaveta A, Xia, Chuanwu, Kim, Jung-Ja, Kovrigin, Evgenii L
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820150/
https://ncbi.nlm.nih.gov/pubmed/29168021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-017-0152-3
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