Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

Acetaminophen (APAP) overdose is the leading cause of acute liver failure. Yet the mechanisms underlying adaptive tolerance toward APAP-induced liver injury are not fully understood. To better understand molecular mechanisms contributing to adaptive tolerance to APAP is an underpinning foundation fo...

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Vydáno v:Arch Toxicol
Hlavní autoři: Yu, Dianke, Wu, Leihong, Gill, Pritmohinder, Tolleson, William H., Chen, Si, Sun, Jinchun, Knox, Bridgett, Jin, Yaqiong, Xiao, Wenming, Hong, Huixiao, Wang, Yong, Ren, Zhen, Guo, Lei, Mei, Nan, Guo, Yongli, Yang, Xi, Shi, Leming, Chen, Yinting, Zeng, Linjuan, Dreval, Kostiantyn, Tryndyak, Volodymyr, Pogribny, Igor, Fang, Hong, Shi, Tieliu, McCullough, Sandra, Bhattacharyya, Sudeepa, Schnackenberg, Laura, Mattes, William, Beger, Richard D., James, Laura, Tong, Weida, Ning, Baitang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820133/
https://ncbi.nlm.nih.gov/pubmed/29067470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2090-y
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