Atypical Dopamine Transporter Inhibitors Attenuate Compulsive-like Methamphetamine Self-Administration in Rats

Methamphetamine (METH) is a highly addictive drug, but no pharmacological treatment is yet available for METH use disorders. Similar to METH, the wake-promoting drug (R)- modafinil (R-MOD) binds to the dopamine transporter (DAT). Unlike METH, R-MOD is not a substrate for transport by DAT and has low...

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Veröffentlicht in:Neuropharmacology
Hauptverfasser: Tunstall, Brendan J., Ho, Chelsea P., Cao, Jianjing, Vendruscolo, Janaína C.M., Schmeichel, Brooke E., Slack, Rachel D., Tanda, Gianluigi, Gadiano, Alexandra J., Rais, Rana, Slusher, Barbara S., Koob, George F., Newman, Amy H., Vendruscolo, Leandro F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820113/
https://ncbi.nlm.nih.gov/pubmed/29217282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.12.006
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