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High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing
Myosins adjust their power outputs in response to mechanical loads in an isoform-dependent manner, resulting in their ability to dynamically adapt to a range of motile challenges. Here, we reveal the structural basis for force-sensing based on near-atomic resolution structures of one rigor and two A...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5819444/ https://ncbi.nlm.nih.gov/pubmed/29358376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718316115 |
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