Force-producing ADP state of myosin bound to actin

Molecular motors produce force when they interact with their cellular tracks. For myosin motors, the primary force-generating state has MgADP tightly bound, whereas myosin is strongly bound to actin. We have generated an 8-Å cryoEM reconstruction of this state for myosin V and used molecular dynamic...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wulf, Sarah F., Ropars, Virginie, Fujita-Becker, Setsuko, Oster, Marco, Hofhaus, Goetz, Trabuco, Leonardo G., Pylypenko, Olena, Sweeney, H. Lee, Houdusse, Anne M., Schröder, Rasmus R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822626/
https://ncbi.nlm.nih.gov/pubmed/26976594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516598113
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