Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis

Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in xenobiotic metabolism. Plexiform neurofibromas (PNFs) can transform into malignant peripheral nerve sheath tumors (MPNSTs) that are resistant to existing therapies. These tumors are primarily composed of Schwann c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Shackleford, Ghjuvan’Ghjacumu, Sampathkumar, Nirmal Kumar, Hichor, Mehdi, Weill, Laure, Meffre, Delphine, Juricek, Ludmila, Laurendeau, Ingrid, Chevallier, Aline, Ortonne, Nicolas, Larousserie, Frédérique, Herbin, Marc, Bièche, Ivan, Coumoul, Xavier, Beraneck, Mathieu, Baulieu, Etienne-Emile, Charbonnier, Frédéric, Pasmant, Eric, Massaad, Charbel
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819423/
https://ncbi.nlm.nih.gov/pubmed/29351992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715999115
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi