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Nilotinib impairs skeletal myogenesis by increasing myoblast proliferation

BACKGROUND: Tyrosine kinase inhibitors (TKIs) are effective therapies with demonstrated antineoplastic activity. Nilotinib is a second-generation FDA-approved TKI designed to overcome Imatinib resistance and intolerance in patients with chronic myelogenous leukemia (CML). Interestingly, TKIs have al...

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Detalhes bibliográficos
Publicado no:Skelet Muscle
Main Authors: Contreras, Osvaldo, Villarreal, Maximiliano, Brandan, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819301/
https://ncbi.nlm.nih.gov/pubmed/29463296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-018-0150-5
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