Improved detection of genetic loci in estimated glomerular filtration rate and type 2 diabetes using a pleiotropic cFDR method

Genome-wide association studies (GWAS) have been shown to have the potential of explaining more of the “missing heritability” of complex human phenotypes by improving statistical approaches. Here, we applied a genetic-pleiotropy-informed conditional false discovery rate (cFDR) to capture additional...

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Vydáno v:Mol Genet Genomics
Hlavní autoři: Liu, Hui-Min, He, Jing-Yang, Zhang, Qiang, Lv, Wan-Qiang, Xia, Xin, Sun, Chang-Qing, Zhang, Wei-Dong, Deng, Hong-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819009/
https://ncbi.nlm.nih.gov/pubmed/29038864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00438-017-1381-6
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