Insulin treatment reverses the increase in atrogin-1 expression in atrophied skeletal muscles of diabetic rats with acute joint inflammation

BACKGROUND: The aim of this study was to evaluate the changes in biomarkers of skeletal muscle proteolysis (atrogin-1, muscle RING finger-1 protein [MuRF-1]) and inflammation (nuclear factor kappa-B) in skeletal muscles of rats under two catabolic conditions, diabetes mellitus (DM) and acute joint i...

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Vydáno v:Ther Clin Risk Manag
Hlavní autoři: Pinheiro-Dardis, Clara Maria, Gutierres, Vânia Ortega, Assis, Renata Pires, Peviani, Sabrina Messa, Delfino, Gabriel Borges, Durigan, João Luiz Quagliotti, Salvini, Tania de Fátima, Baviera, Amanda Martins, Brunetti, Iguatemy Lourenço
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818839/
https://ncbi.nlm.nih.gov/pubmed/29497304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S142948
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