Piperine, a Natural Bioenhancer, Nullifies the Antidiabetic and Antioxidant Activities of Curcumin in Streptozotocin-Diabetic Rats

Knowing that curcumin has low bioavailability when administered orally, and that piperine has bioenhancer activity by inhibition of hepatic and intestinal biotransformation processes, the aim of this study was to investigate the antidiabetic and antioxidant activities of curcumin (90 mg/kg) and pipe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arcaro, Carlos Alberto, Gutierres, Vânia Ortega, Assis, Renata Pires, Moreira, Thais Fernanda, Costa, Paulo Inácio, Baviera, Amanda Martins, Brunetti, Iguatemy Lourenço
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254914/
https://ncbi.nlm.nih.gov/pubmed/25469699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113993
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