Acrolein Disrupts Tight Junction Proteins and Causes Endoplasmic Reticulum Stress-Mediated Epithelial Cell Death Leading to Intestinal Barrier Dysfunction and Permeability

Increasing evidence suggests that environmental and dietary factors can affect intestinal epithelial integrity leading to gut permeability and bacterial translocation. Intestinal barrier dysfunction is a pathogenic process associated with many chronic disorders. Acrolein is an environmental and diet...

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Enregistré dans:
Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Chen, Wei-Yang, Wang, Min, Zhang, Jingwen, Barve, Shirish S., McClain, Craig J., Joshi-Barve, Swati
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818631/
https://ncbi.nlm.nih.gov/pubmed/28935573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.015
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