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Expedient syntheses of N-heterocycles via intermolecular amphoteric diamination of allenes

Saturated 1,4-diazo heterocycles including piperazines, 1,4-diazepanes, and 1,4-diazocanes, are highly important for therapeutic development, but their syntheses are often tedious. We describe here an amphoteric diamination strategy to unite readily available 1,2-, 1,3- or 1,4-diamine derivatives wi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ye, Zhishi, Adhikari, Sarju, Xia, Yu, Dai, Mingji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818626/
https://ncbi.nlm.nih.gov/pubmed/29459667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03085-3
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