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Reduced Orbitofrontal Gray Matter Concentration as a Marker of Premorbid Childhood Trauma in Cocaine Use Disorder

Background: Childhood trauma affects neurodevelopment and promotes vulnerability to impaired constraint, depression, and addiction. Reduced gray matter concentration (GMC) in the mesocorticolimbic regions implicated in reward processing and cognitive control may be an underlying substrate, as docume...

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Detalhes bibliográficos
Publicado no:Front Hum Neurosci
Main Authors: Bachi, Keren, Parvaz, Muhammad A., Moeller, Scott J., Gan, Gabriela, Zilverstand, Anna, Goldstein, Rita Z., Alia-Klein, Nelly
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818418/
https://ncbi.nlm.nih.gov/pubmed/29497369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2018.00051
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