Reduced Orbitofrontal Gray Matter Concentration as a Marker of Premorbid Childhood Trauma in Cocaine Use Disorder

Background: Childhood trauma affects neurodevelopment and promotes vulnerability to impaired constraint, depression, and addiction. Reduced gray matter concentration (GMC) in the mesocorticolimbic regions implicated in reward processing and cognitive control may be an underlying substrate, as docume...

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Veröffentlicht in:Front Hum Neurosci
Hauptverfasser: Bachi, Keren, Parvaz, Muhammad A., Moeller, Scott J., Gan, Gabriela, Zilverstand, Anna, Goldstein, Rita Z., Alia-Klein, Nelly
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818418/
https://ncbi.nlm.nih.gov/pubmed/29497369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2018.00051
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