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Tau Filaments and the Development of Positron Emission Tomography Tracers
A pathological pathway leading from soluble, monomeric to insoluble, filamentous Tau, is believed to underlie human Tauopathies. Cases of frontotemporal dementia are caused by dominantly inherited mutations in MAPT, the Tau gene. They show that dysfunction of Tau protein is sufficient to cause neuro...
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| Veröffentlicht in: | Front Neurol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818396/ https://ncbi.nlm.nih.gov/pubmed/29497399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00070 |
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