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Tau Filaments and the Development of Positron Emission Tomography Tracers

A pathological pathway leading from soluble, monomeric to insoluble, filamentous Tau, is believed to underlie human Tauopathies. Cases of frontotemporal dementia are caused by dominantly inherited mutations in MAPT, the Tau gene. They show that dysfunction of Tau protein is sufficient to cause neuro...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Goedert, Michel, Yamaguchi, Yoshiki, Mishra, Sushil K., Higuchi, Makoto, Sahara, Naruhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818396/
https://ncbi.nlm.nih.gov/pubmed/29497399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00070
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