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Development of optimized conditions for Glaser-Hay bioconjugations

The efficient preparation of protein bioconjugates represents a route to novel materials, diagnostics, and therapeutics. We previously reported a novel bioorthogonal Glaser-Hay reaction for the preparation of covalent linkages between proteins and a reaction partner; however, deleterious protein deg...

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Publicat a:Bioorg Chem
Autors principals: Nimmo, Zachary M., Halonski, John F., Chatkewitz, Lindsay E., Young, Douglas D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818283/
https://ncbi.nlm.nih.gov/pubmed/29227916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2017.11.020
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