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Application of the Solid-Supported Glaser–Hay Reaction to Natural Product Synthesis

The Glaser–Hay coupling of terminal alkynes is a useful synthetic reaction for the preparation of polyynes; however, chemoselectivity issues have precluded its widespread utilization. Conducting the reaction on a solid-support provides a mechanism to alleviate the chemoselectivity issues and provide...

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Bibliographic Details
Published in:J Org Chem
Main Authors: Lampkowski, Jessica S., Uthappa, Diya M., Halonski, John F., Maza, Johnathan C., Young, Douglas D.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455993/
https://ncbi.nlm.nih.gov/pubmed/27978730
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