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Countervailing, time-dependent effects on host autophagy promote intracellular survival of Leishmania

Autophagy is essential for cell survival under stress and has also been implicated in host defense. Here, we investigated the interactions between Leishmania donovani, the main etiological agent of visceral leishmaniasis, and the autophagic machinery of human macrophages. Our results revealed that d...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Thomas, Sneha A., Nandan, Devki, Kass, Jennifer, Reiner, Neil E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818176/
https://ncbi.nlm.nih.gov/pubmed/29269416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808675
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