Adjunct zonisamide to levodopa for DLB parkinsonism: A randomized double-blind phase 2 study

OBJECTIVE: To investigate the efficacy and safety of zonisamide as an adjunct to levodopa therapy for parkinsonism in patients with dementia with Lewy bodies (DLB). METHODS: This phase 2, placebo-controlled, randomized, double-blind study consisted of run-in (placebo, 4 weeks) and treatment (placebo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurology
Prif Awduron: Murata, Miho, Odawara, Toshinari, Hasegawa, Kazuko, Iiyama, Sayaka, Nakamura, Masatoshi, Tagawa, Masaaki, Kosaka, Kenji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818167/
https://ncbi.nlm.nih.gov/pubmed/29367449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005010
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