A carregar...

Schwann cell-specific deletion of the endosomal PI 3-kinase Vps34 leads to delayed radial sorting of axons, arrested myelination, and abnormal ErbB2-ErbB3 tyrosine kinase signaling

The PI 3-kinase Vps34 (Pik3c3) synthesizes phosphatidylinositol 3-phosphate (PI3P), a lipid critical for both endosomal membrane traffic and macroautophagy. Human genetics have implicated PI3P dysregulation, and endosomal trafficking in general, as a recurring cause of demyelinating Charcot-Marie-To...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Glia
Main Authors: Logan, Anne M., Mammel, Anna E., Robinson, Danielle C., Chin, Andrea L., Condon, Alec F., Robinson, Fred L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818149/
https://ncbi.nlm.nih.gov/pubmed/28617998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23173
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!