CCL2/CCL5 secreted by the stroma induce IL-6/PYK2 dependent chemoresistance in ovarian cancer

BACKGROUND: Minimal residual disease is the main issue of advanced ovarian cancer treatment. According to the literature and previous results, we hypothesized that Mesenchymal Stromal Cells (MSC) could support this minimal residual disease by protecting ovarian cancer cells (OCC) from chemotherapy....

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Pasquier, Jennifer, Gosset, Marie, Geyl, Caroline, Hoarau-Véchot, Jessica, Chevrot, Audrey, Pocard, Marc, Mirshahi, Massoud, Lis, Raphael, Rafii, Arash, Touboul, Cyril
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817856/
https://ncbi.nlm.nih.gov/pubmed/29455640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0787-z
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