Surgical peritoneal stress creates a pro-metastatic niche promoting resistance to apoptosis via IL-8

BACKGROUND: The mainstay of treatment of advanced ovarian cancer (AOC) involves chemotherapy, and debulking surgery. However, despite optimal surgical procedure and adjuvant chemotherapy, 60% of patients with AOC will relapse within 5 years. Most recurrences occur in the peritoneal cavity, suggestin...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Pasquier, Jennifer, Vidal, Fabien, Hoarau-Véchot, Jessica, Bonneau, Claire, Daraï, Emile, Touboul, Cyril, Rafii, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171219/
https://ncbi.nlm.nih.gov/pubmed/30285881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1643-z
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