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Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats

OBJECTIVE: Whether activation or inhibition of the mTOR pathway is beneficial to ischemic injury remains controversial. It may result from the different reaction of ischemic penumbra and core to modulation of mTOR pathway after cerebral ischemia–reperfusion injury in rats. METHODS: Longa's midd...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Wu, Meiling, Zhang, Huadan, Kai, Jiejing, Zhu, Feng, Dong, Jingyin, Xu, Ziwei, Wong, Michael, Zeng, Ling‐Hui
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817831/
https://ncbi.nlm.nih.gov/pubmed/29468175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.507
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