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Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats

OBJECTIVE: Whether activation or inhibition of the mTOR pathway is beneficial to ischemic injury remains controversial. It may result from the different reaction of ischemic penumbra and core to modulation of mTOR pathway after cerebral ischemia–reperfusion injury in rats. METHODS: Longa's midd...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Wu, Meiling, Zhang, Huadan, Kai, Jiejing, Zhu, Feng, Dong, Jingyin, Xu, Ziwei, Wong, Michael, Zeng, Ling‐Hui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817831/
https://ncbi.nlm.nih.gov/pubmed/29468175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.507
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