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The rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer
Gene fusions occur in up to 17% of solid tumours. Oncogenic kinases are often involved in such fusions. In lung cancer, almost 30% of patients carrying an activated oncogene show the fusion of a tyrosine kinase to an heterologous gene. Several genes are partner in the fusion with the three kinases A...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817729/ https://ncbi.nlm.nih.gov/pubmed/29455670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0799-8 |
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