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DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data

BACKGROUND: DNA methylation is an epigenetic modification that is studied at a single-base resolution with bisulfite treatment followed by high-throughput sequencing. After alignment of the sequence reads to a reference genome, methylation counts are analyzed to determine genomic regions that are di...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Gaspar, John M., Hart, Ronald P.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817627/
https://ncbi.nlm.nih.gov/pubmed/29187143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1909-0
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