Statistical methods for detecting differentially methylated regions based on MethylCap-seq data

DNA methylation is a well-established epigenetic mark, whose pattern throughout the genome, especially in the promoter or CpG islands, may be modified in a cell at a disease stage. Recently developed probabilistic approaches allow distributing methylation signals at nucleotide resolution from Methyl...

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Bibliographische Detailangaben
Veröffentlicht in:Brief Bioinform
Hauptverfasser: Ayyala, Deepak N., Frankhouser, David E., Ganbat, Javkhlan-Ochir, Marcucci, Guido, Bundschuh, Ralf, Yan, Pearlly, Lin, Shili
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142008/
https://ncbi.nlm.nih.gov/pubmed/26454095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv089
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