Efficacy of combining ING4 and TRAIL genes in cancer-targeting gene virotherapy strategy: first evidence in preclinical hepatocellular carcinoma

Current treatments of hepatocellular carcinoma (HCC) are ineffective and unsatisfactory in many aspects. Cancer-targeting gene virotherapy using oncolytic adenoviruses (OAds) armed with anticancer genes has shown efficacy and safety in clinical trials. Nowadays, both inhibitor of growth 4 (ING4), as...

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Publicado en:Gene Ther
Autores principales: Galal El-Shemi, A, Mohammed Ashshi, A, Oh, E, Jung, B-K, Basalamah, M, Alsaegh, A, Yun, C-O
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817393/
https://ncbi.nlm.nih.gov/pubmed/28925992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.86
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