Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model

BACKGROUND: Gene-based virotherapy mediated by oncolytic viruses is currently experiencing a renaissance in cancer therapy. However, relatively little attention has been given to the potentiality of dual gene virotherapy strategy as a novel therapeutic approach to mediate triplex anticancer combinat...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: El-Shemi, Adel Galal, Ashshi, Ahmad Mohammed, Na, Youjin, Li, Yan, Basalamah, Mohammed, Al-Allaf, Faisal Ahmad, Oh, Eonju, Jung, Bo-Kyeong, YUN, Chae-Ok
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859966/
https://ncbi.nlm.nih.gov/pubmed/27154307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0353-8
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